Towards Laser Driven Hadron Cancer Radiotherapy: A Review of Progress

It has been known for about sixty years that proton and heavy ion therapy is a very powerful radiation procedure for treating tumours. It has an innate ability to irradiate tumours with greater doses and spatial selectivity compared with electron and photon therapy and hence is a tissue sparing procedure. For more than twenty years powerful lasers have generated high energy beams of protons and heavy ions and hence it has been frequently speculated that lasers could be used as an alternative to RF accelerators to produce the particle beams necessary for cancer therapy. The present paper reviews the progress made towards laser driven hadron cancer therapy and what has still to be accomplished to realise its inherent enormous potential.Comment: 40 pages, 24 figure

Orbital electron capture by the nucleus

The theory of nuclear electron capture is reviewed in the light of current understanding of weak interactions. Experimental methods and results regarding capture probabilities, capture ratios, and EC/Beta(+) ratios are summarized. Radiative electron capture is discussed, including both theory and experiment. Atomic wave function overlap and electron exchange effects are covered, as are atomic transitions that accompany nuclear electron capture. Tables are provided to assist the reader in determining quantities of interest for specific cases

In Situ Characterisation of Permanent Magnetic Quadrupoles for focussing proton beams

High intensity laser driven proton beams are at present receiving much attention. The reasons for this are many but high on the list is the potential to produce compact accelerators. However two of the limitations of this technology is that unlike conventional nuclear RF accelerators lasers produce diverging beams with an exponential energy distribution. A number of different approaches have been attempted to monochromise these beams but it has become obvious that magnetic spectrometer technology developed over many years by nuclear physicists to transport and focus proton beams could play an important role for this purpose. This paper deals with the design and characterisation of a magnetic quadrupole system which will attempt to focus and transport laser-accelerated proton beams.Comment: 20 pages, 42 figure

Study of photo-proton reactions driven by bremsstrahlung radiation of high-intensity laser generated electrons

Photo-nuclear reactions were investigated using a high power table-top laser. The laser system at the University of Jena ( I similar to 3-5 x 10(19) W cm(-2)) produced hard bremsstrahlung photons ( kT similar to 2(9 MeV) via a laser-gas interaction which served to induce ( gamma, p) and ( gamma, n) reactions in Mg, Ti, Zn and Mo isotopes. Several ( gamma, p) decay channels were identified using nuclear activation analysis to determine their integral reaction yields

The nuclear AC-Stark shift in super-intense laser fields

The direct interaction of super-intense laser fields in the optical frequency domain with nuclei is studied. As main observable, we consider the nuclear AC-Stark shift of low-lying nuclear states due to the off-resonant excitation by the laser field. We include the case of accelerated nuclei to be able to control the frequency and the intensity of the laser field in the nuclear rest frame over a wide range of parameters. We find that AC-Stark shifts of the same order as in typical quantum optical systems relative to the respective transition frequencies are feasible with state-of-the-art or near-future laser field intensities and moderate acceleration of the target nuclei. Along with this shift, we find laser-induced modifications to the proton root-mean-square radii and to the proton density distribution. We thus expect direct laser-nucleus interaction to become of relevance together with other super-intense light-matter interaction processes such as pair creation.Comment: 10 pages, 2 eps figure

Plasma–wall interaction in laser inertial fusion reactors: novel proposals for radiation tests of first wall materials

Dry-wall laser inertial fusion (LIF) chambers will have to withstand strong bursts of fast charged particles which will deposit tens of kJ m−2 and implant more than 1018 particles m−2 in a few microseconds at a repetition rate of some Hz. Large chamber dimensions and resistant plasma-facing materials must be combined to guarantee the chamber performance as long as possible under the expected threats: heating, fatigue, cracking, formation of defects, retention of light species, swelling and erosion. Current and novel radiation resistant materials for the first wall need to be validated under realistic conditions. However, at present there is a lack of facilities which can reproduce such ion environments. This contribution proposes the use of ultra-intense lasers and high-intense pulsed ion beams (HIPIB) to recreate the plasma conditions in LIF reactors. By target normal sheath acceleration, ultra-intense lasers can generate very short and energetic ion pulses with a spectral distribution similar to that of the inertial fusion ion bursts, suitable to validate fusion materials and to investigate the barely known propagation of those bursts through background plasmas/gases present in the reactor chamber. HIPIB technologies, initially developed for inertial fusion driver systems, provide huge intensity pulses which meet the irradiation conditions expected in the first wall of LIF chambers and thus can be used for the validation of materials too